|Botanical Name||Punica granatum|
|Parts Used||Dried seed and fruit|
Anti-diarrhoeal activity- exhibits intestinal anti-secretory activity. Anti-ulcer activity - significantly decreases gastric lesions. Anti-hyperlipidemic activity - surpasses triglyceride synthesis in liver through inhibition of fatty acid synthase; reduces serum triglyceride, total cholesterol and LDL levels; decreases cholesterol absorption and affects HMG-CoA reductase. Anti-obesity effect - shows to cause decrease in body weight and improve serum lipid profile. Anti-diabetic effect - mildly reduces plasma glucose levels; increases tissue sensitivity towards insulin; inhibits diabetes-induced inflammatory processes; improves lipid profile. Nephroprotective effect - produces vasodilation and increases blood flow in kidneys; reduces oxidative stress. Effect on preeclampsia - shows protective effect on endothelial cells of preeclamptic patients. Hepatoprotective effect - due to its antioxidant and anti-inflammatory effects as well as inhibition of collagen synthesis, shows to protect against liver fibrosis. Ergogenic effect - shows to enhance vessel diameter, blood flow and delay fatigue during exercises. Anti-atherosclerotic effect - protects endothelial function, improves lipid profile. Anti-hypertensive effect - inhibits serum angiotensin converting enzyme (ACE) and decreases systolic blood pressure. Cardioprotective effect - prevents cardiac damage; reduces myocardial ischemia and improves myocardial perfusion; shows significant therapeutic value in prophylactic treatment of myocardial infarction.
Anti-microbial activity- shows antibacterial activity (against Proteus spp., H.influenza, Klebsiella pneumoniae, Pseudomonas aeruginosa, Streptococcus spp., Staphylococcus aureus, Enterocuccus faecalis, E.coli); anti-fungal activity (Candida albicans, Trichophyton spp.); antiviral activity (against genital herpes virus, Herpes simplex virus, hepatitis B virus, hepatitis C virus); anti-parasitic activity (Taenia spp., Ascaris lumbricoides); shows to inhibit oral pathogens. Immunomodulatory effect Anti-inflammatory activity - reduces levels of pro-inflammatory cytokines; inhibits COX, LOX. Anti-acne activity - inhibits growth of acne-related bacteria; down-regulates sebum production by reducing lipase activity; attenuates the inflammatory status; prevents keratinocyte over-proliferation. Anti-osteoporotic effect - shows to promote bone cell proliferation and differentiation in primary osteoblasts; inhibits bone resorption process. Anti-rheumatoid arthritis effect - exhibits anti-inflammatory effect; prevents development of joint damage; prevents maintenance and development of inflammation in RA; reduces severity and incidence of joint inflammation; inhibits cartilage degradation; helps to maintain joint integrity and function. Antioxidant activity - inhibits lipid peroxidation; protects from oxidative stress; has free radical scavenging activity. Neuroprotective activity - inhibits cholinesterase activity; prevents accumulation of lipid in brain; protects brain from stress oxidant; protects against cerebral ischemia-reperfusion induced oxidative brain injury; inhibits learning and memory deficits and neuronal cell death caused by amyloid-beta-induced oxidative stress; thus may be beneficial for prevention, management and supportive treatment of neurodegenerative diseases; shows to reduce neuropathic pain in acquired peripheral neuropathy. Anti-cancer activity - shows to be chemopreventive/ chemotherapeutic agent; exhibits anti-inflammatory, anti-proliferative and anti-tumorigenic effects on skin, breast, prostate, lung and colon cancers.
Rejuvenation action:Balances cold and Wind disorders Strengthens lungs Restores physical strength and warmth Increases libido and potency Supports heart function Treats anemia
Gastrointestinal system:Restores digestive heat Relieves indigestion Reduces gastric acidity Relieves gastrointestinal irritation Balances appetite Stops nausea and vomiting Stops diarrhoea Clears constipation Relieves thirst and dryness Heals mouth and gastrointestinal ulcers Relieves haemorrhoids Clears parasites
Genitourinary system:Strengthens the kidneys Clears vaginal infection Normalizes menstrual flow
Immune system and detoxification:Clears lung fever Treats bronchitis and other respiratory tract infections Relieves shortness of breath Strengthens immune system Clears skin
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